仅用于工业应用或科学研究，不可用于人类或动物的临床诊断或治疗，非药用. Teprotumumab is an IGF-1 receptor （IGF-1R） blocking human monoclonal antibody. Teprotumumab binds to the ligand binding extracellular α-subunit domain of IGF-1R. Teprotumumab inhibits TSH and IGF-1 action in fibrocytes. Teprotumumab attenuates TSH-dependent IL-6 and IL-8 expression and Akt phosphorylation. Teprotumumab can be used for thyroid-associated ophthalmopathy research
产品型号：1036734-93-6
更新时间：2024-03-20
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